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Item number: Cay19134-1

Proprotein convertase subtilisin kexin 9 (PCSK9) is a member of the subtilisin serine protease family with important roles in lipoprotein metabolism. PCSK9 overexpression in wild-type mice doubles plasma total cholesterol, possibly through acceleration of degradation of the LDL receptor (LDLR). SBC-115076 is an...

Keywords:	1,5-dihydro-3-hydroxy-4-[3-methyl-4-(phenylmethoxy)benzoyl]-1-[3-(4-morpholinyl)propyl]-5-(4-pyridinyl)-2H-pyrrol-2-one
Application:	PCSK9 inhibitor
CAS	489415-96-5
MW:	527.6 D

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SBC-115076

Item number: TGM-T2626-100mg

Description: SBC-115076 is a potent extracellular proprotein convertase subtilisin kexin type 9 (PCSK9) antagonist. Target: Serine/threonin kinase, Others. Smiles: Cc1cc(ccc1OCc1ccccc1)C(=O)C1=C(O)C(=O)N(CCCN2CCOCC2)C1c1ccncc1. References: Abdel-Meguid SS, et al. WO2014150326 A1.

Keywords:	SBC115076
Application:	PCSK9 inhibitor
CAS	489415-96-5
MW:	527.61 D

From 33.00€ *

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