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AZD2858
AZD2858

Item number: TGM-T1957-100mg

Description: AZD2858 is a selective GSK-3 inhibitor, inhibiting tau phosphorylation at the S396 site and activating Wnt signaling pathway. Target: GSK-3. Smiles: C(NC=1C=CC=NC1)(=O)C=2N=C(C=NC2N)C3=CC=C(S(=O)(=O)N4CCN(C)CC4)C=C3. References: Marsell R, et al. Bone, 2012, 50(3), 619-627.
Application: GSK3beta inhibitor
CAS 486424-20-8
MW: 453.52 D
From 33.00€ *
Review
AZD 2858
AZD 2858

Item number: Cay16728-1

Glycogen synthase kinase 3beta (GSK3beta) was originally identified for its ability to constitutively phosphorylate and inactivate glycogen synthase, preventing glycogen synthesis. It can also phosphorylate proteins that are relevant to osteogenesis and Alzheimer's disease, the latter for which it has earned the...
Keywords: 3-amino-6-[4-[(4-methyl-1-piperazinyl)sulfonyl]phenyl]-N-3-pyridinyl-2-pyrazinecarboxamide
Application: GSK3beta inhibitor
CAS 486424-20-8
MW: 453.5 D
From 45.00€ *
Review