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PAZ-417
Item number: Cay42122-1
A PAI-1 inhibitor (IC50 = 655 nM), selective for PAI-1 over tPA and plasminogen, as well as a panel of 40 neurotransmitter, endocrine, and enzymatic targets, at 10 µM, enhances cleavage of monomeric and oligomeric Abeta42 in a cell-free assay at 5 µM, reduces plasma Abeta40 and brain Abeta40 and Abeta42 levels in...
| Keywords: | Aleplasinin, 1-[[4-(1,1-dimethylethyl)phenyl]methyl]-5-(3-methylphenyl)-a-oxo-1H-indole-3-acetic acid |
| Application: | PAI-1 inhibitor |
| CAS | 481629-87-2 |
| MW: | 425.5 D |
From 53.00€
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Aleplasinin
Item number: TGM-T29856-100mg
Description: Aleplasinin (PAZ 417) is a selective and orally active inhibitor of Plasminogen activator inhibitor-1(PAI-1) and a key negative regulator of the fibrinolytic system. Aleplasinin can be used in Alzheimer's disease studies. Target: Beta Amyloid, PAI-1. Smiles:...
| Keywords: | PAZ-417 , PAZ 417 , PAZ417 |
| CAS | 481629-87-2 |
| MW: | 425.52 D |
From 49.00€
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