Description: Taxifolin (Dihydroquercetin) is a flavonoid in many plants such as Taxus chinensis, Siberian larch, Cedrus deodara and so on. Target: VEGFR, TNF, Adrenergic Receptor, Autophagy, Tyrosinase. Smiles: O[C@@H]1[C@H](Oc2cc(O)cc(O)c2C1=O)c1ccc(O)c(O)c1. References: Makena PS, et al. Environ Mol Mutagen,...

Taxifolin is a catechol-type flavonoid that displays cardioprotective, neuroprotective, antioxidative, and anticancer chemotherapeutic activities. In animal models of diabetic cardiomyopathy, taxifolin inhibits myocyte apoptosis (through inhibition of caspase-3 and caspase-9 activation, release of cytochrome c, and...

(+)-Taxifolin is a flavonol with antioxidant activity. It increases cell viability of FeCl2 and H2O2-treated bone marrow-derived mesenchymal stem cells (bmMSCs) when used at concentrations ranging from 1 to 100 µg/ml. It also scavenges PTIO radicals in a pH-dependent manner with lower concentrations needed at higher...