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Item number: Cay19077-5

GSK3beta Inhibitor II is a potent inhibitor of glycogen synthase kinase-3beta (GSK3beta, IC50 = 390 nM) that does not inhibit GSK-3alpha. Also referred to as tip-oxadiazole, this compound blocks the functional regulation of p53 by GSK3beta, decreasing levels of MDM2, p21, and Bax and modulating mitochondrial p53...

Keywords:	Glycogen Synthase Kinase 3beta Inhibitor II, Tip-oxadiazole, 4-[5-[[(3-iodophenyl)methyl]thio]-1,3,4-oxadiazol-2-yl]-pyridine
Application:	GSK-3 beta inhibitor
CAS	478482-75-6
MW:	395.2 D

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