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Item number: Cay42222-10

An agonist of alpha7 nAChRs, selective for alpha7 nAChRs over alpha4beta2-, alpha4beta4-, alpha3beta2-, or alpha3beta4 subunit-containing nAChRs and 5-HT3 (EC50s = 0.03, >100, >50, >100, >100, and 11 µM, respectively, in calcium mobilization assays), prevents decreases in the number of retinal ganglion cells in a...

Keywords:	PHA-543,613, N-(3R)-1-azabicyclo[2.2.2]oct-3-yl-furo[2,3-c]pyridine-5-carboxamide
Application:	alpha7 nAChR agonist
CAS	478149-53-0
MW:	271.31 D

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PHA 543613

Item number: TGM-T23145-100mg

Description: PHA 543613 is a specific agonist of alpha7 nAChR (Ki = 8.8 nM) and can be used in studies about the cognitive deficits of Alzheimer's disease and schizophrenia. Target: Others, AChR. Smiles: O=C(N[C@H]1CN2CCC1CC2)c1cc2ccoc2cn1. References: Donn G Wishka, et al. Discovery of...

CAS	478149-53-0
MW:	271.31 D

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