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Item number: TGM-T14337-100mg

Description: Buloxibutid (AT2 receptor agonist C21) is a novel and selective small molecule angiotensin II AT2 receptor agonist, exhibiting Ki values of 0.4 nM and 10 µM for AT2 and AT1 receptors, respectively. Target: RAAS. Smiles: CCCCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(Cn2ccnc2)cc1. References: Wan Y, et al....

Keywords:	AT2 receptor agonist C21
Application:	AT2 receptor agonist
CAS	477775-14-7
MW:	475.62 D

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AT2 Agonist C21

Item number: Cay33758-1

AT2 agonist C21 is an agonist of the angiotensin II type 2 (AT2) receptor. It selectively binds to the AT2 receptor over the AT1 receptor (Kis = 0.4 and >10 µM, respectively). AT2 agonist C21 (0.1 µM) induces neurite outgrowth in NG 108-15 cells. It reduces mean arterial blood pressure in anaesthetized spontaneously...

Keywords:	Compound 21, N-[[3-[4-(1H-imidazol-1-ylmethyl)phenyl]-5-(2-methylpropyl)-2-thienyl]sulfonyl]-carbamic acid, butyl ester
Application:	AT2 receptor agonist
CAS	477775-14-7
MW:	475.6 D

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