- Search results for 476159-98-5
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2 products were found matching "476159-98-5"!
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Item number: TGM-T14487-2mg
Description: AZM475271 is a potent and selective inhibitor of Src kinase (IC50: 5 nM). Target: Others. Smiles: COc1ccc(Cl)c(Nc2ncnc3cc(OCC4CCN(C)CC4)c(OC)cc23)c1. References: Plé PA, et al. Discovery of a new class of anilinoquinazoline inhibitors with high affinity and specificity for the tyrosine kinase domain of...
Keywords: | M475271 |
Application: | c-Src kinase inhibitor |
CAS | 476159-98-5 |
MW: | 442.94 D |
From 30.00€
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Item number: Cay37378-10
AZM475271 is an inhibitor of c-Src kinase (IC50 = 0.01 µM). It inhibits phosphorylation of c-Src kinase, Lck, c-Yes, and VEGFR2 (IC50s = 0.01, 0.03, 0.08, and 0.7 µM, respectively). AZM475271 inhibits proliferation of NIH3T3 fibroblasts, as well as PC3 and DU145 prostate and A549 lung cancer cells (IC50s = 0.5, 32,...
Keywords: | M475271, N-(2-chloro-5-methoxyphenyl)-6-methoxy-7-[(1-methyl-4-piperidinyl)methoxy]-4-quinazolinamine |
Application: | c-Src kinase inhibitor |
CAS | 476159-98-5 |
MW: | 442.9 D |
From 116.00€
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