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NVP-AEW541
NVP-AEW541

Item number: LKT-N8561.1

IGF-1R inhibitor.
Keywords: AEW-541
Application: IGF-1R inhibitor
CAS 475489-16-8
MW: 439.55 D
From 116.00€ *
Review
NVP-AEW541
NVP-AEW541

Item number: TGM-T6080-10mg

Description: NVP-AEW541 (AEW541), a potent inhibitor of IGF-1R(IC50=150 nM) and InsR(IC50=140 nM), exhibits excellent efficiency and specificity for IGF-1R in a cell-based assay. Target: Tyrosine Kinases, IGF-1R, FLT, Autophagy. Smiles: Nc1ncnc2n(cc(-c3cccc(OCc4ccccc4)c3)c12)C1CC(CN2CCC2)C1. References:...
Keywords: AEW541
Application: IGF-1R inhibitor
CAS 475489-16-8
MW: 439.55 D
From 35.00€ *
Review
NVP-AEW541
NVP-AEW541

Item number: Cay33946-10

NVP-AEW541 is an inhibitor of insulin-like growth factor 1 receptor (IGF-1R, IC50 = 0.15 µM in a cell-free assay). It is selective for IGF-1R over a panel of 20 kinases but also inhibits the insulin receptor (InsR), VEGFR1, FMS-related tyrosine kinase 3 (FLT3), and tunica interna endothelial cell kinase 2 (Tie2,...
Keywords: 7-[cis-3-(1-azetidinylmethyl)cyclobutyl]-5-[3-(phenylmethoxy)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine
Application: IGF-1R inhibitor
CAS 475489-16-8
MW: 439.6 D
From 172.00€ *
Review