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NVP-ADW742
Item number: TGM-T6079-100mg
Description: NVP-ADW742 (ADW) is an IGF-1R inhibitor with IC50 of 0.17 µM, >16-fold more potent against IGF-1R than InsR, little activity to HER2, PDGFR, VEGFR-2, Bcr-Abl and c-Kit. Target: IGF-1R, Apoptosis. Smiles: Nc1ncnc2n(cc(-c3cccc(OCc4ccccc4)c3)c12)C1CC(CN2CCCC2)C1. References: Mitsiades CS, et al. Cancer...
| Keywords: | ADW, GSK 552602A, ADW742 |
| Application: | IGF-1R inhibitor |
| CAS | 475488-23-4 |
| MW: | 453.58 D |
From 48.00€
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NVP-ADW742
Item number: Cay18390-1
NVP-ADW742 is an insulin-like growth factor 1 receptor (IGF-1R) inhibitor with an IC50 value of 0.17 µM. It exhibits 6-fold greater selectivity for IGF-1R over the insulin receptor (InsR) kinase and minimal inhibitory activity against c-Kit, HER1, PDGFR, VEGFR2, or Bcr-Abl p210. NVP-ADW742 has been shown to inhibit...
| Keywords: | ADW742, GSK552602A,... |
| Application: | IGF-1R inhibitor |
| CAS | 475488-23-4 |
| MW: | 453.6 D |
From 49.00€
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