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Item number: TGM-T74583-10mg

Description: Desmethylazelastine, the primary active metabolite of Azelastine, undergoes oxidative metabolism via the cytochrome P450 enzyme system, exhibits a 97% protein binding rate, and has an elimination half-life of 54 hours. Azelastine, an orally active, selective, and high-affinity histamine H1-receptor...

Application:	Azelastine active metabolite
CAS	47491-38-3
MW:	367.87 D

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N-desmethyl Azelastine

Item number: Cay35429-1

N-desmethyl Azelastine is an active metabolite of the histamine H1 receptor antagonist azelastine (Cay-20873). It is formed from azelastine primarily by the cytochrome P450 (CYP) isoforms CYP3A4 and CYP2D6 and, to a lesser extent, by CYP1A2. N-desmethyl Azelastine (1 µM) inhibits acetylcholine-induced depolarization...

Keywords:	DAZ, Desmethylazelastine, 4-[(4-chlorophenyl)methyl]-2-(hexahydro-1H-azepin-4-yl)-1(2H)-phthalazinone
Application:	Azelastine active metabolite
CAS	47491-38-3
MW:	367.9 D

From 69.00€ *

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