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Kartogenin
Kartogenin

Item number: TGM-T1748-100mg

Description: Kartogenin (KGN) is an activator of the smad4/smad5 pathway, and promotes the selective differentiation of multipotent mesenchymal stem cells into chondrocytes. Target: TGF-beta/Smad. Smiles: OC(=O)c1ccccc1C(=O)Nc1ccc(cc1)-c1ccccc1. References: Johnson K, et al. Science. 2012, 336(6082), 717-721.
Keywords: KGN
Application: Chondrogenesis inducer
CAS 4727-31-5
MW: 317.34 D
From 31.00€ *
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Kartogenin
Kartogenin

Item number: Cay11826-10

Kartogenin potently induces differentiation of human mesenchymal stem cells into chondrocytes with an EC50 value of 100 nM. Kartogenin induces chondrogenesis by binding the actin-binding protein, filamin A, which disrupts its interaction with the transcription factor core-binding factor beta subunit (CBFbeta). When...
Keywords: 2-[([1,1'-biphenyl]-4-ylamino)carbonyl]-benzoic acid
Application: Chondrogenesis inducer
CAS 4727-31-5
MW: 317.3 D
From 87.00€ *
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Kartogenin
Kartogenin

Item number: LKT-K0271.25

Collagen synthesis stimulator.
Application: Collagen synthesis stimulator
CAS 4727-31-5
MW: 317.34 D
From 128.00€ *
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