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Marinobufagenin
Item number: Cay20798-1
Marinobufagenin (MBG) is a bufadienolide steroid first isolated from toads of genus Bufo. It can also be excreted by mammalian cells, particularly kidney cells from hypertensive animals. MBG inhibits the ouabain-resistant alpha1 Na+/K+ ATPase subunit (IC50 = 78 nM), impairing a major sodium pump of the kidneys,...
| Keywords: | Marinobufagin, MBG, NSC 234205, (3beta,5beta,15beta)-14,15-epoxy-3,5-dihydroxy-bufa-20,22-dienolide |
| Application: | ATP1A1 inhibitor |
| CAS | 470-42-8 |
| MW: | 400.5 D |
From 85.00€
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Marinobufogenin
Item number: TGM-TN1912-1mg
Description: Marinobufagenin, a cardiotonic steroid, its increased concentrations are important in the cardiac disease and oxidant stress state seen with renal failure. Target: ATPase, EGFR. Smiles: [H][C@@]12CC[C@]3(O)C[C@@H](O)CC[C@]3(C)[C@@]1([H])CC[C@]1(C)[C@H](C[C@H]3O[C@@]213)c1ccc(=O)oc1. References:...
| Keywords: | Marinobufagenin |
| CAS | 470-42-8 |
| MW: | 400.51 D |
From 187.00€
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