Description: Lactulose (Lactulosum) , a synthetic disaccharide , is used in the treatment of constipation and hepatic encephalopathy. Target: Others. Smiles: OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O. References: Algieri F, et al. J Agric Food Chem. 2014 May 14, 62(19):4285-97.

Lactulose is a synthetic and non-digestible sugar. It reduces colonic pH to 3.5 and stimulates circular muscle activity and propulsion of fluid in isolated guinea pig ileum and colon. Formulations containing lactulose have been used to treat constipation.Formal Name: 4-O-beta-D-galactopyranosyl-D-fructose. CAS...

A keto analogue of lactose. Primary bile acids are converted to carcinogenic secondary bile acids by colonic bacteria when the colonic pH is high. Addition of lactulose to the diet of experimental animals showed a significant fall in small intestinal and colonic pH. In humans lactulose reduced dehydroxylation of...