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Item number: Cay45575-1

ABT-239 is a histamine H3 receptor antagonist (Kis = 0.316 and 1.258 nM, respectively, for the human and rat receptors). In vivo, ABT-239 (0.1-1 mg/kg) inhibits the dipsogenic response induced by (R)-(-)-alpha-methylhistamine (Cay25601) in mice. It improves social memory in adult and aged rats and attenuates...

Keywords:	4-[2-[2-[(2R)-2-methyl-1-pyrrolidinyl]ethyl]-5-benzof uranyl]-benzonitrile
Application:	Histamine H3 receptor antagonist
CAS	460746-46-7
MW:	330.43 D

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ABT-239

Item number: TGM-T14087-100mg

Description: ABT-239 is a novel, highly efficacious non-imidazole class histamine H3 receptor (H3R) antagonist and also acts as a transient receptor potential vanilloid type 1 (TRPV1) antagonist. Target: TRP/TRPV Channel. Smiles: C[C@@H]1CCCN1CCc1cc2cc(ccc2o1)-c1ccc(cc1)C#N. References: Bhowmik M, et al. Histamine...

CAS	460746-46-7
MW:	330.42 D

From 38.00€ *

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Review

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