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Item number: Cay19118-5

ONO-8130 is an orally bioavailable antagonist of the prostaglandin E2 (PGE2) receptor EP1 (Ki = 1.9 nM) It exerts a more than 1,000-fold selectivity for EP1 compared with other EP receptors. ONO-8130 suppresses pain associated with cyclophosphamide-induced cystitis in mice at 0.3-30 mg/kg. It also blocks...

Keywords:	4-[[[2,3-dihydro-6-[(2-methylpropyl)[(4-methyl-2-thiazolyl)sulfonyl]amino]-1H-inden-5-yl]oxy]methyl]-benzoic acid
Application:	PTGER1 antagonist
CAS	459841-96-4
MW:	500.6 D

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ONO-8130

Item number: TGM-T21976-10mg

Description: ONO-8130 is an orally available antagonist of EP1 receptor. Target: Prostaglandin Receptor. Smiles: N(S(=O)(=O)C=1SC=C(C)N1)(CC(C)C)C2=C(OCC3=CC=C(C(O)=O)C=C3)C=C4C(=C2)CCC4. References: Miki T , Matsunami M , Nakamura S , et al. ONO-8130, a selective prostanoid EP1 receptor antagonist, relieves bladder...

CAS	459841-96-4
MW:	500.63 D

From 152.00€ *

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