3 products were found matching "459789-99-2"!
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6-ECDCA
Item number: AG-CR1-3560-M005
Potent and selective farnesoid X receptor FXR agonist (EC50= 99nM) [1]. Induces SHP in HSCs to suppress TIMP-1 expression [2]. Apoptosis inducer [2]. Protects against liver fibrosis development in rat in vivo [2]. Displays anticholeretic activity in rat in vivo [3]. Promotes preadipocyte differentiation [4]....
| Keywords: | 6alpha-Ethyl-chenodeoxycholic acid, 6-alpha-ECDC, Obeticholic acid, INT-747, OCA |
| Application: | FXR agonist |
| CAS | 459789-99-2 |
| MW: | 420,3 D |
From 22.00€
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6-ECDCA
Item number: Cay11031-5
Farnesoid X receptor (FXR) is a nuclear receptor that is activated by bile acid, with chenodeoxycholic acid (CDCA) being a representative natural ligand. 6-ECDCA is a synthetic bile acid that acts as a potent and selective agonist of FXR (EC50 = 99 nM). Through FXR, it alters gene expression that results in...
| Keywords: | INT 747, Obeticholic Acid, (3alpha,5beta,6alpha,7alpha)-6-ethyl-3,7-dihydroxy-cholan-24-oic acid |
| Application: | FXR agonist |
| CAS | 459789-99-2 |
| MW: | 420.6 D |
From 38.00€
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Obeticholic Acid
Item number: TGM-T1789-50mg
Description: Obeticholic Acid (6-ECDCA) is a Farnesoid X Receptor Agonist. The mechanism of action of obeticholic acid is as a Farnesoid X Receptor Agonist. Target: Autophagy, FXR. Smiles: CC[C@H]1[C@@H](O)[C@H]2[C@@H]3CC[C@H]([C@H](C)CCC(O)=O)[C@@]3(C)CC[C@@H]2[C@@]2(C)CC[C@@H](O)C[C@@H]12. References: Pellicciari...
| Keywords: | INT-747, 6-Ethylchenodeoxycholic acid, 6-ECDCA |
| Application: | Targets farnesoid X receptor (NR1H4, FXR) |
| CAS | 459789-99-2 |
| MW: | 420.63 D |
From 39.00€
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