MJN228 is a selective ligand for the lipid-binding protein nucleobindin 1 (NUCB1), blocking binding of the probe arachidonoyl ethanolamide-diazirine with an IC50 value of 3.3 µM. It prevents probe binding to NUCB1 in Neuro2a cells at concentrations as low as 10 µM. MJN228 has been used to elucidate the role of NUCB1...

Description: MJN228 is a lipid-binding protein nucleobindin-1 (NUCB1) inhibitor that blocks the AEA-DA probe labeling of endogenous NUCB1 in Neuro2a cells and can be used for the study of metabolic disorders. Target: Others. Smiles: O=C(N1CCN(CC1)C)C2=C(C3=CC=CC=C3)C4=C(C=CC([N+]([O-])=O)=C4)N2