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Item number: Cay35836-10

AA92593 is an opsin 4 (OPN4) receptor antagonist (Ki = 16 nM). It inhibits light-induced calcium transients in CHO cells expressing human OPN4 (IC50 = 665 nM). AA92593 (10 µM) reverses light-induced calcium influx in rat intrinsically photosensitive retinal ganglion cells (ipRGCs). In vivo, AA92593 (30 mg/kg)...

Keywords:	1-[(4-methoxy-3-methylphenyl)sulfonyl]-piperidine
Application:	OPN4 receptor antagonist
CAS	457961-34-1
MW:	269.4 D

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AA92593

Item number: TGM-T8566-100mg

Description: AA92593 has been used as a selective inhibitor of melanopsin. Target: Others. Smiles: COc1ccc(cc1C)S(=O)(=O)N1CCCCC1. References: Alkozi H A , Wang X , Jesus P D L M , et al. Presence of melanopsin in human crystalline lens epithelial cells and its role in melatonin synthesis[J]. Experimental Eye...

Application:	OPN4 receptor antagonist
CAS	457961-34-1
MW:	269.36 D

From 45.00€ *

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