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(S)-H-1152 (hydrochloride)
Item number: Cay10007653-1
Rho-associated kinase (ROCK), activated by GTP-linked Rho, phosphorylates targets that are involved in cytoskeletal remodeling, smooth muscle contraction, and neuronal development. H-1152 is a potent, specific, ATP-competitive, and cell permeable inhibitor of ROCK (Ki = 1.6 nM). It is a more potent inhibitor of ROCK...
| Keywords: | 5-[[(2S)-hexahydro-2-methyl-1H-1,4-diazepin-1-yl]sulfonyl]-4-methyl-isoquinoline, dihydrochloride |
| Application: | ROCK inhibition |
| CAS | 451462-58-1 |
| MW: | 392.3 D |
From 54.00€
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H-1152
Item number: TGM-T7552-10mg
Description: H-1152 is a potent, specific, ATP-competitive, and cell permeable ROCK inhibitor (Ki = 1.6 nM). Target: ROCK. Smiles: S(=O)(=O)(C=1C2=C(C=CC1)C=NC=C2C)N3[C@@H](C)CNCCC3. References: Ikenoya M , Hidaka H , Hosoya T , et al. Inhibition of Rho-kinase-induced myristoylated alanine-rich C kinase substrate...
| Application: | ROCK inhibition |
| CAS | 451462-58-1 |
| MW: | 319.42 D |
From 120.00€
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