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Item number: Cay43814-1

TH301 is a stabilizer of cryptochrome circadian regulator 2 (CRY2). It selectively stabilizes CRY2 over CRY1 in a degradation assay using HEK293 cells expressing CRY reporters at 0. to 10 µM. TH301 lengthens the circadian period in wild-type but not Cry2-/- mouse fibroblasts. It enhances rosiglitazone-dependent...

Keywords:	1-(4-chlorophenyl)-N-[2,6-dihydro-2-(4-methoxyphenyl)-5,5-dioxido-4H-thieno[3,4-c]pyrazol-3-yl]-cyclopentanecarboxamide
Application:	CRY2 stabilizer
CAS	450338-32-6
MW:	485.98 D

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