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Item number: Cay26743-1

CP 671,305 is a potent inhibitor of phosphodiesterase 4D (PDE4D, IC50 = 3 nM). It is selective for PDE4D over PDE4A, -B, and -C (IC50s = 310, 287, and 3,858 nM, respectively), as well as over PDE1-3 and 5 (IC50s = >5,000 nM for all). CP 671,305 inhibits release of leukotriene E4 (LTE4, Cay-20410) from eosinophils...

Keywords:	(2R)-2-[4-[[[[2-(1,3-benzodioxol-5-yloxy)-3-pyridinyl]carbonyl]amino]methyl]-3-fluorophenoxy]-propanoic acid
Application:	PDE4D inhibitor
CAS	445295-04-5
MW:	454.4 D

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