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Cyclopamine
Item number: Cay11321-10
Cyclopamine is a natural steroidal alkaloid that inhibits signaling through the hedgehog pathway at the level of the pathway activator Smoothened. By altering gene expression in this signaling sequence, cyclopamine induces defects in morphogenesis, first observed in chicks and sheep as cyclopia. As a readout of...
| Keywords: | 11-Deoxojervine, Jervine,... |
| Application: | Pax7 inhibitor |
| CAS | 4449-51-8 |
| MW: | 411.6 D |
From 32.00€
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Cyclopamine
Item number: TGM-T2825-100mg
Description: Cyclopamine (11-Deoxojervine), a Smoothened (Smo) antagonist (IC50: 46 nM in TM3Hh12 cells), belongs to the group of steroidal jerveratrum alkaloids. Target: Endogenous Metabolite, Hedgehog/Smoothened, Smo. Smiles:...
| Keywords: | 11-Deoxojervine |
| Application: | Biochemical studies |
| CAS | 4449-51-8 |
| MW: | 411.62 D |
From 48.00€
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Cyclopamine
Item number: LKT-C9710.5
A steroidal alkaloid isolated from the desert plant Veratrum californicum with both teratogenic and antitumor activities. It inhibits hedgehog/smoothened signaling.
| Keywords: | 11-Deoxyjervine, 11-Deoxojervine, HSDB 3505., Spiro(9H-benzo(a)fluorene-9,2'(3'H)-furo(3,2-b)pyridin)-3- ol,... |
| Application: | Metabolic studies, Hedgehog inhibitor |
| CAS | 4449-51-8 |
| MW: | 411,62 D |
From 118.00€
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Cyclopamine
Item number: AG-CN2-0028-M005
A steroidal alkaloid isolated from the desert plant Veratrum californicum with both teratogenic and antitumor activities. It inhibits hedgehog/smoothened signaling.
| Keywords: | 11-Deoxyjervine, 11-Deoxojervine, HSDB 3505 |
| Application: | Biochemical studies |
| CAS | 4449-51-8 |
| MW: | 411,6 kD |
From 36.00€
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