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p38alpha MAPK-IN-1
p38alpha MAPK-IN-1

Item number: Cay40839-10

p38alpha MAPK-IN-1 is an inhibitor of p38alpha MAPK (IC50 = 5,500 nM in a homogeneous time-resolved fluorescence (HTRF) assay). It inhibits TNF-alpha production induced by LPS in THP-1 cells (EC50 = 6,200 nM). p38alpha MAPK-IN-1 has been used in the study of p38alpha MAPK inhibitor binding interactions and...
Keywords: p38alpha MAPK Inhibitor 1, p38alpha Mitogen-activated Protein Kinase Inhibitor 1, p38alpha Mitogen-activated Protein...
Application: P38alpha MAPK inhibitor
CAS 443913-15-3
MW: 477.6 D
From 186.00€ *
Review
p38-alpha MAPK-IN-1
p38-alpha MAPK-IN-1

Item number: TGM-T12347-100mg

Description: p38-alpha MAPK-IN-1 is a MAPK14 (p38-alpha) inhibitor with an IC50 of 2300 nM in the EFC displacement assay and 5500 nM in the HTRF assay. Target: p38 MAPK, Autophagy. Smiles: Cc1ccc(cc1)-n1nc(cc1NC(=O)Nc1ccc(OCCN2CCOCC2)cc1)C(C)(C)C. References: Kluter S, et al. Displacement assay for the detection of...
Application: P38alpha MAPK inhibitor
CAS 443913-15-3
MW: 477.6 D
From 76.00€ *
Review