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Vipadenant
Vipadenant

Item number: Cay20239-1

Vipadenant is a selective adenosine 2A (A2A) receptor antagonist with Ki values of 1.3, 68, 63, and 1,005 nM for A2A, A1, A2B, and A3 receptors, respectively, in a radioligand binding assay. It acts as a functional antagonist of human recombinant A2A (KA = 0.58 nM) in a calcium mobilization-based FLIPR assay....
Keywords: BIIB-014, 3-[(4-amino-3-methylphenyl)methyl]-7-(2-furanyl)-3H-1,2,3-triazolo[4,5-d]pyrimidin-5-amine
Application: Adenosine A2A receptor antagonist
CAS 442908-10-3
MW: 321.3 D
From 94.00€ *
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Vipadenant
Vipadenant

Item number: TGM-T2373-100mg

Description: Vipadenant (CEB-4520)(BIIB-014) is an adenosine A2a antagonist with Ki of 1.3 nM, less potent for A1(Ki=69 nM). Target: Adenosine Receptor. Smiles: Cc1cc(Cn2nnc3c(nc(N)nc23)-c2ccco2)ccc1N. References: Jones N, et al. A2A receptor antagonists do not induce dyskinesias in drug-naive or L-dopa sensitized...
Keywords: CEB-4520, BIIB-014
CAS 442908-10-3
MW: 321.34 D
From 34.00€ *
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