4 products were found matching "439081-18-2"!
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Forskolin
Item number: BPS-27068
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| Keywords: | forskolin, Coleonol, |
| Application: | Adenylate cyclase activator |
| CAS | 439081-18-2 |
| MW: | 410.5 D |
507.00€
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Forskolin
Item number: BPS-27067
Forskolin is a cell permeable adenylate cyclase activator which causes an increase in the intracellular concentration of cAMP. This makes it an important hypotensive and vasodilatory agent. Forskolin also affects calcium currents and inhibits PKC (Protein Kinase C)-stimulated MAPK and RAF-1.
| Application: | Cell-permeable adenylate cyclase activator |
| CAS | 439081-18-2 |
| MW: | 410.5 D |
389.00€
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Afatinib
Item number: SYN-1100-M001
Soluble in DMSO or ethanol. Afatinib is an irreversible kinase inhibitor and binds to the kinase domains of EGFR (ErbB1), HER2 (ErbB2), and HER4 (ErbB4) to inhibit tyrosine kinase autophosphorylation. This results in a downregulation of ErbB signaling and subsequent inhibition of proliferation of cell lines...
| Keywords: | Tovok, BIBW-2992 |
| Application: | EGFR / HER2 inhibitor |
| CAS | 439081-18-2 |
| MW: | 486 D |
From 123.00€
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NEW
(S)-Afatinib
Item number: TGM-T2303-1mL
Description: (S)-Afatinib (BIBW2992) is an irreversible EGFR family inhibitor with IC50s of 0.5/0.4/10/14/1 nM for EGFRwt, EGFR (L858R), EGFR (L858R/T790M), HER2, and HER4, respectively. Target: Autophagy, c-Met/HGFR, HER, EGFR, p38 MAPK, Apoptosis, Akt. Smiles:...
| Keywords: | BIBW2992 |
| CAS | 439081-18-2 |
| MW: | 485.94 D |
From 29.00€
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