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PFK15
PFK15

Item number: Cay17689-5

6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3) is a bifunctional enzyme that contains distinct domains for the phosphorylation of fructose 6-phosphate and the dephosphorylation of fructose 2,6-bisphosphate. PFKFB3 protein expression is elevated in most tumor types. PFK15 is a selective inhibitor of...
Keywords: 1-(4-pyridinyl)-3-(2-quinolinyl)-2-propen-1-one
Application: PFKFB3 inhibitor
CAS 4382-63-2
MW: 260.3 D
From 67.00€ *
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PFK-015
PFK-015

Item number: TGM-T2455-100mg

Description: PFK-015 (PFK15) is an effective inhibitor of PFKFB3 (IC50: 110 nM) and inhibits PFKFB3 activity in Y cells (IC50: 20 nM). Target: Glucokinase, Autophagy. Smiles: O=C(\C=C\c1ccc2ccccc2n1)c1ccncc1. References: Clem BF, et al. Mol Cancer Ther. 2013, 12(8), 1461-1470.
Keywords: PFK 015, PFK15
CAS 4382-63-2
MW: 260.29 D
From 34.00€ *
Review