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(S)-PHA-533533
(S)-PHA-533533

Item number: Cay45337-1

(S)-PHA-533533 is an inhibitor of cyclin-dependent kinase 2 (Cdk2)/cyclin A, Cdk2/cyclin E, Cdk5/p25, and Cdk1/cyclin B complexes and glycogen synthase kinase 3beta (GSK3beta, IC50s = 37, 55, 65, 208, and 732 nM, respectively, in cell-free assays). It selectively inhibits these complexes and GSK3beta over the...
Keywords: N-(5-cyclopropyl-1H-pyrazol-3-yl)-alphaS-methyl-4-(2-oxo-1-pyrrolidinyl)-benzeneacetamide
Application: Cdk2/cyclin A inhibitor
CAS 437982-89-3
MW: 338.41 D
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