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Item number: AG-CN2-0444-C100

Potent, irreversible inhibitor of all the 3 proteolytic activities of the mammalian 20S proteasome. beta5 subunit: chymotrypsin-like (EC50 = 3.5nM) beta2 subunit: trypsin-like (EC50 = 28nM) beta1 subunit: caspase-like or peptidyl-glutamyl peptide-hydrolyzing (PGPH) (EC50 = 430nM) Potent anticancer compound. Triggers...

Keywords:	SalA, Marizomib, NPI-0052
Application:	Potent irreversible mammalian 20S proteasome subunit beta1/2/5 inhibitor
CAS	437742-34-2
MW:	313,8 D

From 143.00€ *

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Salinosporamide A

Item number: Cay10007311-100

Salinosporamide A is a natural proteasome inhibitor. It is a beta-lactone-gamma-lactam that irreversibly inhibits all three protease activities within the proteasome (IC50s = 3.5, 28, and 430 nM for beta5 (chymotrypsin), beta2 (macropain), and beta1 (C5) subunits, respectively), both in vitro and in vivo....

Keywords:	Marizomib, ML-858, NPI-0052,...
Application:	Natural proteasome inhibitor, PSMB5 / PSMB2 / PSMB1 inhibitor
CAS	437742-34-2
MW:	313.8 D

222.00€ *

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