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Dacarbazine
Item number: TGM-T1120-100mg
Description: Dacarbazine (DTIC-Dome) is an antineoplastic agent. It has significant activity against melanomas. Target: Nucleoside Antimetabolite/Analog, Apoptosis, DNA/RNA Synthesis. Smiles: N(=NN(C)C)C1=C(C(N)=O)N=CN1. References: Serrone L, et al. J Exp Clin Cancer Res. 2000, 19(1):21-34.
| Keywords: | DTIC-Dome, Imidazole Carboxamide |
| CAS | 4342-03-4 |
| MW: | 182.18 D |
From 33.00€
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Dacarbazine
Item number: LKT-D0011.100
Dacarbazine is used in the treatment of malignant melanoma and sarcomas.
| Application: | Cancer studies |
| CAS | 4342-03-4 |
| MW: | 182,18 D |
From 120.00€
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Dacarbazine
Item number: Cay21877-500
Dacarbazine is a DNA alkylating prodrug that is activated by P450 enzymes in liver microsomes. Following activation, it is converted, through a series of reactions, into a methyldiazonium cation that alkylates DNA at all phases of the cell cycle and induces apoptosis. In vitro, dacarbazine inhibits the growth of...
| Keywords: | NCI C04717, NSC 45388, 5-(3,3-dimethyl-1-triazen-1-yl)-1H-imidazole-4-carboxamide |
| Application: | DNA alkylating prodrug |
| CAS | 4342-03-4 |
| MW: | 182.2 D |
From 74.00€
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