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BRD32048
Item number: Cay16516-1
ETS variant 1 (ETV1) is a transcription factor oncogene implicated in several cancers where it has been altered by chromosomal translocation, gene amplification, or lineage dysregulation. The ETV1 transcription factor is phosphorylated downstream of MAPK signaling and is acetylated at lysines 33 and 116 by the...
| Keywords: | N2-(4-methoxyphenyl)-6-(1-piperidinylmethyl)-1,3,5-triazine-2,4-diamine |
| Application: | ETV1 inhibitor |
| CAS | 433694-46-3 |
| MW: | 314.4 D |
From 44.00€
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BRD32048
Item number: TGM-T23820-5mg
Description: BRD32048 is a top candidate ETV1 perturbagen. BRD32048 inhibits p300-dependent acetylation of ETV1, thereby promoting its degradation. Target: DNA/RNA Synthesis. Smiles: COc1ccc(Nc2nc(N)nc(CN3CCCCC3)n2)cc1. References: Kollareddy M, Sherrard A, Park JH, Szemes M, Gallacher K, Melegh Z, Oltean S,...
| Keywords: | BRD 32048, BRD-32048 |
| CAS | 433694-46-3 |
| MW: | 314.39 D |
From 38.00€
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