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SMI-6860766
Item number: Cay42960-1
SMI-6860766 is an inhibitor of the protein-protein interaction between TNF receptor-associated factor 6 (TRAF6) and CD40. It binds to TRAF1, TRAF2, TRAF3, and TRAF6 (Kds = 52, 30, 37, and 59 µM, respectively). SMI-6860766 inhibits LPS-induced increases in the levels of NF-kappaB in RAW 264. macrophages (IC50 = 0....
| Keywords: | 3-[(4-bromo-2-chlorophenyl)amino]-1-phenyl-2-propen-1-one |
| Application: | TRAF6-CD40 protein-protein interaction inhibitor |
| CAS | 433234-16-3 |
| MW: | 336.61 D |
From 35.00€
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SMI-6860766
Item number: TGM-T24808-100mg
Description: SMI-6860766 is a CD40-Traf6 interactions blocker that acts by ameliorating the complications of diet-induced obesity in mice. Target: Others. Smiles: ClC1=CC(Br)=CC=C1N\C=C\C(=O)C1=CC=CC=C1. References: van den Berg SM, Seijkens TT, Kusters PJ, Zarzycka B, Beckers L, den Toom M, Gijbels MJ,...
| Keywords: | TRAF-STOP 6860766, SMI6860766, TRAFSTOP6860766, SMI 6860766, TRAFSTOP 6860766 |
| CAS | 433234-16-3 |
| MW: | 336.61 D |
From 1,520.00€
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