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4E2RCat
Item number: TGM-T14044-100mg
Description: 4E2RCat is an inhibitor of eIF4E-eIF4G interaction (IC50 = 13.5 µM) and effectively blocks coronavirus replication, as evidenced by reduced viral protein expression and decreased production of infectious virus. Target: PERK. Smiles: OC(=O)c1cc(ccc1Cl)-c1ccc(\C=C2/SC(=S)N(Cc3ccccc3)C2=O)o1. References:...
| Application: | eIF4E-eIF4G protein-protein interaction inhibitor |
| CAS | 432499-63-3 |
| MW: | 455.93 D |
From 58.00€
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4E2RCat
Item number: Cay35894-10
4E2RCat is an inhibitor of the protein-protein interaction between eukaryotic translation initiation factor 4E (eIF4E) and eIF4G (IC50 = 13.5 µM). It reduces mRNA translation without inducing apoptosis in L-132 cells when used at a concentration 12.5 µM. 4E2RCat (6 µM) decreases intracellular and extracellular...
| Keywords: | 2-chloro-5-[5-[[4-oxo-3-(phenylmethyl)-2-thioxo-5-thiazolidinylidene]methyl]-2-furanyl]-benzoic acid |
| Application: | eIF4E-eIF4G protein-protein interaction inhibitor |
| CAS | 432499-63-3 |
| MW: | 455.9 D |
From 35.00€
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