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Cladribine
Item number: Cay12085-10
Cladribine is a nucleoside analog of deoxyadenosine and prodrug form of 2-chlorodeoxyadenosine triphosphate (2-CdATP). It is triphosphorylated to Cd-ATP by the successive actions of deoxycytidine kinase, nucleoside monophosphate kinase, and nucleoside diphosphate kinase. Cladribine is cytotoxic to resting or...
| Keywords: | 2-Chlorodeoxyadenosine, Biodribin, Jk 6251, Leustatin, NSC 105014, RWJ 26251, 2-chloro-2'-deoxy-adenosine |
| Application: | Nucleoside analog, lymphocyte cytotoxic |
| CAS | 4291-63-8 |
| MW: | 285.7 D |
From 34.00€
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Cladribine
Item number: LKT-C4402.5
A nucleoside analogue that was found to induce DNA double-strand breaks and cell death in log-phase Chinese hamster V79 cells.
| Application: | Metabolic studies |
| CAS | 4291-63-8 |
| MW: | 285,69 D |
From 128.00€
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Cladribine
Item number: TGM-T2558-100mg
Description: Cladribine (2CdA), an adenosine deaminase inhibitor, is utilized in the treatment of lymphoproliferative diseases. Target: Adenosine deaminase, Apoptosis. Smiles: Nc1nc(Cl)nc2n(cnc12)[C@H]1C[C@H](O)[C@@H](CO)O1. References: Ma J, et al. BMC Cancer. 2011, 11, 255.
| Keywords: | 2-Chloro-2'-deoxyadenosine, CldAdo, 2-chlorodeoxyadenosine, 2CdA |
| Application: | Targets ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1] (RRM1) |
| CAS | 4291-63-8 |
| MW: | 285.69 D |
From 33.00€
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