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Item number: TGM-T21767-100mg

Description: MS37452 is a competitive inhibitor of CBX7 chromodomain binding to H3K27me3 (Ki = 43 µM). Target: Others, Histone Methyltransferase. Smiles: COc1cccc(C(=O)N2CCN(CC2)C(=O)COc2cccc(C)c2)c1OC. References: Chunyan Ren, et al.Small-Molecule Modulators of Methyl-Lysine Binding for the CBX7 Chromodomain.Chem...

CAS	423748-02-1
MW:	398.45 D

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MS37452

Item number: Cay17533-1

Chromobox homolog 7 (CBX7) functions through its N-terminal chromodomain, which recognizes histone 3 trimethyl lysine 27 (H3K27me3), to repress gene transcription. It plays a key role in gene transcription in cellular processes related to stem cell self-renewal and differentiation, as well as tumor progression....

Keywords:	1-[4-(2,3-dimethoxybenzoyl)-1-piperazinyl]-2-(3-methylphenoxy)-ethanone
Application:	Competitive CBX7 chromodomain H3K27me3 binding inhibitor
CAS	423748-02-1
MW:	398.5 D

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