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ML-161
Item number: Cay15179-1
ML-161 is an allosteric, reversible inhibitor of proteinase-activated receptor 1 (PAR1) on platelets, preventing surface expression of P-selectin induced by the peptide SFLLRN with an IC50 value of 0.26 µM. It blocks platelet activation induced by thrombin as well as by SFLLRN but not by PMA (Cay-10008014), U-46619...
| Keywords: | AG-670, CID-1048267, 2-bromo-N-[3-[(1-oxobutyl)amino]phenyl]-benzamide |
| Application: | PAR1 inhibitor |
| CAS | 423735-93-7 |
| MW: | 361.2 D |
From 49.00€
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Parmodulin 2
Item number: TGM-T1893-100mg
Description: Parmodulin 2 (ML 161) is the inhibitor of protease-activated receptor 1 (PAR1)-mediated platelet activation (IC50: 0.26 µM for the inhibition of platelet P-selectin expression on human platelets). It also inhibits thrombin-induced platelet activation. Target: Protease-activated Receptor. Smiles:...
| Keywords: | ML 161 |
| Application: | PAR1 inhibitor |
| CAS | 423735-93-7 |
| MW: | 361.23 D |
From 30.00€
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