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Item number: Cay21496-10

MLR-1023 is an allosteric activator of Lyn kinase (EC50 = 63 nM). It has no significant activity against a panel of related kinases. MLR-1023 is orally bioavailable and reduces blood glucose levels in mice subjected to an oral glucose tolerance test. This effect is insulin-dependent, with MLR-1023 increasing insulin...

Keywords:	CP 26,154, NSC 314335, 5-(3-methylphenoxy)-2(1H)-pyrimidinone
Application:	Allosteric Lyn kinase activator
CAS	41964-07-2
MW:	202.2 D

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Tolimidone

Item number: TGM-T6896-100mg

Description: Tolimidone (NSC 314335) is a chemical compound which inhibits acid secretion in animal models and also acts as a bronchodilator in histamine-challenged animals. Target: Src. Smiles: Cc1cccc(Oc2cnc(=O)[nH]c2)c1. References: Saporito MS, et al. J Pharmacol Exp Ther. 2012, 342(1):15-22.

Keywords:	MLR-1023, NSC 314335, CP-26154
Application:	Targets tyrosine-protein kinase Lyn [EC:2.7.10.2] (LYN)
CAS	41964-07-2
MW:	202.21 D

From 41.00€ *

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