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RI-1
Item number: Cay24182-1
RI-1 is an irreversible inhibitor of RAD51 (IC50s = 5-30 µM), a protein that is central to homologous recombination during DNA repair and is overexpressed in a wide range of human cancer cell types. RI-1 selectively inhibits homologous recombination without inhibiting single strand annealing. It binds directly to...
| Keywords: | 3-chloro-1-(3,4-dichlorophenyl)-4-(4-morpholinyl)-1H-pyrrole-2,5-dione |
| Application: | RAD51 inhibitor |
| CAS | 415713-60-9 |
| MW: | 361.6 D |
From 51.00€
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RI-1
Item number: TGM-T2276-100mg
Description: RI-1 (RAD51 inhibitor 1) is a RAD51 inhibitor (IC50: 5-30 µM). Target: DNA/RNA Synthesis. Smiles: ClC1=C(N2CCOCC2)C(=O)N(C1=O)c1ccc(Cl)c(Cl)c1. References: Budke B, et al. Nucleic Acids Res. 2012, 40(15), 7347-7357.
| Keywords: | RAD51 inhibitor 1, RI1 |
| CAS | 415713-60-9 |
| MW: | 361.61 D |
From 36.00€
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