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Item number: Cay71200-10

The pro-angiogenic factor HIF-1alpha is targeted for destruction in normoxic environments by the hydroxylation of a specific proline residue, P564, by the oxygen-sensing enzyme HIF-alpha prolyl hydroxylase (HIF-PH). 2,4-DPD is a cell permeable, competitive inhibitor of HIF-PH. 2,4-DPD inhibits the hydroxylation of...

Keywords:	2,4-Diethylpyridine dicarboxylate, 2,4-pyridinedicarboxylic acid, diethyl ester
Application:	HIF-PH inhibitor
CAS	41438-38-4
MW:	223.2 D

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