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Item number: Cay10012609-5

Terminally misfolded proteins, recognized by chaperones on the endoplasmic reticulum (ER), are transported to depots for ubiquitination and proteasomal degradation by the ER-associated protein degradation (ERAD) pathway. Eeyarestatin 1 is an inhibitor of the ERAD pathway, blocking the degradation of misfolded...

Keywords:	3-(4-chlorophenyl)-4-[[[(4-chlorophenyl)amino]carbonyl] hydroxyamino]-5,5-dimethyl-2-oxo-1- imidazolidineacetic acid...
Application:	ERAD pathway inhibitor, ataxin-3 inhibitor
CAS	412960-54-4
MW:	630.4 D

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Eeyarestatin I

Item number: TGM-T27240-25mg

Description: Eeyarestatin I is an inhibitor that inhibits the degradation and translocation of ER-associated proteins. Eeyarestatin I is associated with the p97 deubiquitination process and inhibits atx3 deubiquitination. Eeyarestatin I has anticancer effects by inducing proteins that cause cell death. Target:...

CAS	412960-54-4
MW:	630.44 D

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