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Item number: Cay42088-1

O4I4 is an inducer of octamer-binding transcription factor 4 (Oct4). It is also an antagonist of chemokine (C-C motif) receptor 4 (CCR4, IC50 = 0.26 µM). O4I4 induces transactivation of Oct4 and Nanog in a reporter assays using NCCIT pluripotent stem cells. It increases the lifespans of C. elegans and Drosophila...

Keywords:	Oct4-inducing Compound 4, 4-(1,1-dimethylethyl)-N-(2,3-dimethylphenyl)-2-thiazolamine
Application:	POU domain, class 5, transcription factor 1 (POU5F1, Oct4) inducer, CCR4 antagonist
CAS	412008-21-0
MW:	260.4 D

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