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Item number: Cay45457-1

Tracazolate is a positive allosteric modulator of the GABAA receptor (GABAAR). It potentiates GABA-stimulated currents in X. laevis oocytes expressing alpha1beta3gamma2s and alpha1beta1delta subunit-containing GABAARs (EC50s = 1.5 and 16.7 µM, respectively) and increases the maximal response to GABA in X. laevis...

Keywords:	ICI 136753, 4-(butylamino)-1-ethyl-6-methyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid, ethyl ester
Application:	GABAA receptor positive allosteric modulator
CAS	41094-88-6
MW:	304.39 D

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