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JNJ-16259685
Item number: Cay35377-1
JNJ-16259685 is an antagonist of metabotropic glutamate receptor 1a (mGluR1a, Ki = 0.34 nM in CHO(dHFr-) cell membranes expressing the rat receptor). It is selective for mGluR1a over mGluR5, -2, -3, -4, and -6, as well as a panel of neurotransmitter receptors, ion channels, and transporters, at 10 µM. JNJ-16259685...
| Keywords: | (3,4-dihydro-2H-pyrano[2,3-b]quinolin-7-yl)(cis-4-methoxycyclohexyl)-methanone |
| Application: | MGluR1a antagonist |
| CAS | 409345-29-5 |
| MW: | 325.4 D |
From 50.00€
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JNJ16259685
Item number: TGM-T5512-100mg
Description: JNJ16259685 (TN.T 16259685) is a selective mGluR1 antagonist, and inhibits the synaptic activation of mGluR1 in a concentration-dependent manner with IC50 of 19 nM. Target: GluR. Smiles: CO[C@H]1CC[C@H](CC1)C(=O)c1ccc2nc3OCCCc3cc2c1. References: Hodgson RA, et al. Characterization of the selective...
| Keywords: | .TN.T 16259685 |
| Application: | MGluR1a antagonist |
| CAS | 409345-29-5 |
| MW: | 325.4 D |
From 39.00€
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