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MDL 72222
MDL 72222

Item number: Cay43507-10

A 5-HT3 receptor antagonist (IC50 = 0.82 nM), selective for 5-HT3 over 5-HT1 and 5-HT2 receptors and alpha1-, alpha2-, and beta-adrenergic receptors (IC50s = >10,000 nM for all), as well as the histamine H1 receptor (IC50 = 3,800 nM), intraplantar administration inhibits formalin-induced paw licking and complete...
Keywords: Bemesetron, 3,5-dichloro-benzoic acid, (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester
Application: 5-HT3 receptor antagonist
CAS 40796-97-2
MW: 314.21 D
From 83.00€ *
Review
Bemesetron
Bemesetron

Item number: TGM-T14526-10mg

Description: Bemesetron (MDL 72222) is a selective 5-HT3 antagonist (IC50 = 0.33 nM) that exhibits neuroprotective effects. Target: 5-HT Receptor. Smiles: CN1[C@@H]2CC[C@@H]1CC(C2)OC(=O)c1cc(Cl)cc(Cl)c1. References: Peters JA, et al. An electrophysiological investigation of the properties of 5-HT3 receptors of...
Keywords: TROPANYL 3,5-DICHLOROBENZOATE, 3-TROPANYL-3,5-DICHLOROBENZOATE, MDL 72222
Application: Targets 5-hydroxytryptamine receptor 3 (HTR3)
CAS 40796-97-2
MW: 314.21 D
From 48.00€ *
Review