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Item number: Cay21922-5

CaCC(inh)-A01 is a non-selective inhibitor of calcium-activated chloride channels (CaCCs) that blocks ATP-stimulated chloride conductance in human salivary gland, intestinal, and bronchial epithelium (mean IC50 = 10 µM). CaCC(inh)-A01 (30 µM) induces full vasorelaxation of preconstricted mouse isolated mesenteric...

Keywords:	TMEM16 Blocker I, 6-(1,1-dimethylethyl)-2-[(2-furanylcarbonyl)amino]-4,5,6,7-tetrahydro-benzo[b]thiophene-3-carboxylic acid
Application:	CaCC inhibitor
CAS	407587-33-1
MW:	347.4 D

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CaCCinh-A01

Item number: TGM-T4330-100mg

Description: CaCCinh-A01 is an inhibitor of the calcium-activated chloride channel (CaCC, 10 µM) and TMEM16A (IC50: 2.1 µM). Target: Chloride channel. Smiles: CC(C)(C)C1CCc2c(C1)sc(NC(=O)c1ccco1)c2C(O)=O. References: Namkung W,etal.TMEM16A inhibitors reveal TMEM16A as a minor component of calcium-activated...

Application:	CaCC inhibitor
CAS	407587-33-1
MW:	347.43 D

From 49.00€ *

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