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Item number: Cay14504-1

ACHP is an inhibitor of IkappaB kinase beta (IKKbeta) and IKKalpha (IC50s = 8.5 and 250 nM, respectively). It is selective for IKKbeta and IKKalpha over IKKgamma, Syk, and MKK4 (IC50s = >20 µM for all). It reduces the constitutive phosphorylation of IkappaBalpha and NF-kappaB p65 in U266 and NCU-MM-2 multiple...

Keywords:	2-amino-6-[2-(cyclopropylmethoxy)-6-hydroxyphenyl]-4-(4-piperidinyl)-3-pyridinecarbonitrile
Application:	IKKbeta / IKKalpha inhibitor
CAS	406208-42-2
MW:	364.4 D

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