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GW3965 hydrochloride
Item number: TGM-T6310-100mg
Description: GW3965 hydrochloride (GW3965 HCl) is an effective and specific LXR agonist for hLXRalpha/beta (EC50: 190/30 nM). Target: Liver X Receptor. Smiles: c1ccc(cc1)C(CN(CCCOc1cccc(c1)CC(=O)O)Cc1c(c(ccc1)C(F)(F)F)Cl)c1ccccc1.Cl. References: Collins JL, et al. J Med Chem. 2002, 45(10), 1963-1966.
| Keywords: | GW3965 HCl |
| Application: | LXR alpha / beta agonist |
| CAS | 405911-17-3 |
| MW: | 618.51 D |
From 35.00€
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GW 3965 (hydrochloride)
Item number: Cay10054-1
The liver X receptors, LXRalpha and LXRbeta, are nuclear receptors that act as ligand-dependent transcription factors. They modulate cholesterol, fatty acids, and glucose homeostasis. GW 3965 is an orally-active agonist of LXRalpha and LXRbeta, activating the human isoforms with EC50 values of 190 and 30 nM,...
| Keywords: | 3-[3-[[[2-chloro-3-(trifluoromethyl)phenyl]methyl](2,2-diphenylethyl)amino]propoxy]-benzeneacetic acid, monohydrochloride |
| Application: | LXR alpha / beta agonist |
| CAS | 405911-17-3 |
| MW: | 618.5 D |
From 34.00€
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