3 products were found matching "405169-16-6"!

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Dovitinib, Free Base (4-Amino-5-fluoro-3-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-2(1H)-qui

Item number: D9060.10

Dovitinib is a small-molecule multi-targeted receptor tyrosine kinase inhibitor. Dovitinib inhibited Ba/F3 cells transformed to IL3 independence by ZNF198-FGFR1 or BCR-FGFR1 with IC50 values of 150nM and 90nM, respectively. The phosphorylation of each fusion gene, ERK, and STAT5 was inhibited as well at the same...

CAS	405169-16-6
MW:	392.43

249.00€ *

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Dovitinib

Item number: Cay15220-10

Dovitinib is a multi-kinase inhibitor. It inhibits the receptor tyrosine kinases FLT3, CSF1R, and c-Kit (IC50s = 1, 36, and 2 nM, respectively), as well as FGFR1, FGFR3, VEGFR1-3, PDFGRalpha, and PDGFRbeta (IC50s = 8, 9, 10, 13, 8, 27, and 210 nM, respectively). Dovitinib inhibits proliferation of human multiple...

Keywords:	CHIR-258, TKI-258, 4-amino-5-fluoro-3-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-2(1H)-quinolinone
Application:	PDGFRB / VEGFR2 / FGFR1 inhibitor
CAS	405169-16-6
MW:	392.4 D

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Dovitinib, Free Base (CHIR-258, TKI-258, CAS...

Item number: LC-D-3608_100mg

Soluble in DMSO

Keywords:	4-amino-5-fluoro-3-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-2(1H)-quinolinone
Application:	PDGFRB / VEGFR2 / FGFR1 inhibitor
CAS	405169-16-6
MW:	392,43 D

From 122.00€ *

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