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Item number: Cay36481-10

4'-Demethylpodophyllotoxin is a lignan that has been found in D. versipellis and has microtubule assembly inhibitory and anticancer activities. It inhibits the assembly of isolated chicken brain tubulin (IC50 = 0.5 µM) and the proliferation of LNCaP and PC3 prostate cancer cells (IC50s = 0.056 and 0.082 µM,...

Keywords:	(5R,5aR,8aR,9R)-5,8,8a,9-tetrahydro-9-hydroxy-5-(4-hydroxy-3,5-dimethoxyphenyl)-furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6...
Application:	Lignan, microtubule assembly inhibitor
CAS	40505-27-9
MW:	400.4 D

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4'-Demethylpodophyllotoxin

Item number: TGM-T2S0029-100mg

Description: 4'-Demethylpodophyllotoxin is isolated from the herb of Dysosma pleiantha (Hance) Woodson with remarkable cytotoxic potential in diverse cancer cell lines. Target: Others. Smiles: COc1cc(cc(OC)c1O)[C@H]1[C@@H]2[C@H](COC2=O)[C@@H](O)c2cc3OCOc3cc12. References: Zilla M K , Nayak D , Amin H , et al....

CAS	40505-27-9
MW:	400.38 D

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