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N-Desmethyl imatinib
Item number: TGM-T11641-100mg
Description: N-Desmethyl imatinib (Imatinib metabolite N-Desmethyl imatinib) is a metabolite of Imatinib, which is a multi-target inhibitor of c-Kit, v-Abl, and PDGFR. Target: Drug Metabolite, Bcr-Abl, PDGFR, c-Kit. Smiles: Cc1ccc(NC(=O)c2ccc(CN3CCNCC3)cc2)cc1Nc1nccc(n1)-c1cccnc1. References: Darweesh RS, et al....
| Keywords: | Imatinib metabolite N-Desmethyl imatinib, Norimatinib |
| CAS | 404844-02-6 |
| MW: | 479.58 D |
From 83.00€
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N-desmethyl Imatinib
Item number: Cay16947-5
N-desmethyl Imatinib is a major active metabolite of imatinib (Cay-13139), an anticancer agent that selectively targets tyrosine kinases, including Bcr-ABL, platelet-derived growth factor receptor (PDGFR), and KIT. N-desmethyl Imatinib is formed when imatinib undergoes demethylation by the cytochrome P450 (CYP)...
| Keywords: | N-Desmethyl Gleevec, STI-509-00,... |
| Application: | Major active imatinib metabolite, tyrosine kinase inhibitor |
| CAS | 404844-02-6 |
| MW: | 479.6 D |
From 53.00€
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